Molecular characterization of an MLL1 fusion and its role in chromosomal instability

Chromosomal rearrangements involving the mixed‐lineage leukemia (MLL1) gene are common in a unique group of acute leukemias, with more than 100 fusion partners in this malignancy alone. However, do these fusions occur or have a role in solid tumors? We performed extensive network analyses of MLL1‐fu...

Descripción completa

Detalles Bibliográficos
Autores principales: Parameswaran, Sreejit, Vizeacoumar, Frederick S., Kalyanasundaram Bhanumathy, Kalpana, Qin, Fujun, Islam, Md. Fahmid, Toosi, Behzad M., Cunningham, Chelsea E., Mousseau, Darrell D., Uppalapati, Maruti C., Stirling, Peter C., Wu, Yuliang, Bonham, Keith, Freywald, Andrew, Li, Hui, Vizeacoumar, Franco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360371/
https://www.ncbi.nlm.nih.gov/pubmed/30548174
http://dx.doi.org/10.1002/1878-0261.12423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360371/
https://www.ncbi.nlm.nih.gov/pubmed/30548174
http://dx.doi.org/10.1002/1878-0261.12423

Ejemplares similares