Targeting the BIR Domains of Inhibitor of Apoptosis (IAP) Proteins in Cancer Treatment

Inhibitor of apoptosis (IAP) proteins are characterized by the presence of the conserved baculoviral IAP repeat (BIR) domain that is involved in protein-protein interactions. IAPs were initially thought to be mainly responsible for caspase inhibition, acting as negative regulators of apoptosis, but...

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Detalles Bibliográficos
Autores principales: Cossu, Federica, Milani, Mario, Mastrangelo, Eloise, Lecis, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360406/
https://www.ncbi.nlm.nih.gov/pubmed/30766663
http://dx.doi.org/10.1016/j.csbj.2019.01.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360406/
https://www.ncbi.nlm.nih.gov/pubmed/30766663
http://dx.doi.org/10.1016/j.csbj.2019.01.009

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