Oxidized Vitamin C (DHA) Overcomes Resistance to EGFR-targeted Therapy of Lung Cancer through Disturbing Energy Homeostasis

Switching aerobic respiration to anaerobic glycolysis of cancer cells plays an important role in development and progression of acquired resistance. Since vitamin C enabled the inhibition of glycolysis of cancer cells, and erlotinib-resistant sub-line of HCC827 (ER6 cells) switched its metabolic fea...

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Detalles Bibliográficos
Autores principales: Ye, Mingtong, Pang, Nengzhi, Wan, Ting, Huang, Yuanling, Wei, Tianyi, Jiang, Xuye, Zhou, Yujia, Huang, Yufeng, Yang, Hainan, Zhang, Zhenfeng, Yang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360421/
https://www.ncbi.nlm.nih.gov/pubmed/30719175
http://dx.doi.org/10.7150/jca.28087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360421/
https://www.ncbi.nlm.nih.gov/pubmed/30719175
http://dx.doi.org/10.7150/jca.28087

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