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Imperatorin Suppresses Anaphylactic Reaction and IgE-Mediated Allergic Responses by Inhibiting Multiple Steps of FceRI Signaling in Mast Cells: IMP Alleviates Allergic Responses in PCA

This study is to investigate the effects of imperatorin (IMP) on allergic responses mediated by mast cells, both in vitro and in vivo. Passive cutaneous anaphylaxis (PCA) model was established. Histological detection was performed to assess the ear histology. ELISA and Western blot analysis were use...

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Detalles Bibliográficos
Autores principales: Xian, Zhemin, Jin, Guangyu, Li, Hongmei, Jiang, Jingzhi, Wang, Chongyang, Zhu, Lianhua, Jin, Zhehu, Li, Liangchang, Piao, Hongmei, Zheng, Mingyu, Yan, Guanghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360561/
https://www.ncbi.nlm.nih.gov/pubmed/30800677
http://dx.doi.org/10.1155/2019/7823761