Proanthocyanidins Antagonize Arsenic-Induced Oxidative Damage and Promote Arsenic Methylation through Activation of the Nrf2 Signaling Pathway

PURPOSE: To investigate the effects of grape seed proanthocyanidin extract (GSPE) on oxidative damage and arsenic (As) methylation and to clarify the role of Nrf2 in the process. METHODS: L-02 cells were treated with arsenic (25 μM) and GSPE (10, 25, and 50 mg/L) for 24 h. Cell viability was analyze...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Mengchuan, Niu, Qiang, Hu, Yunhua, Feng, Gangling, Wang, Haixia, Li, Shugang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360624/
https://www.ncbi.nlm.nih.gov/pubmed/30805085
http://dx.doi.org/10.1155/2019/8549035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360624/
https://www.ncbi.nlm.nih.gov/pubmed/30805085
http://dx.doi.org/10.1155/2019/8549035

Ejemplares similares