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Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma

BACKGROUND: Carcinomas of the small bowel are rare tumors usually with dismal prognosis. Most recently, some potentially treatable molecular alterations were described. We emphasize the growing evidence of individualized treatment options in small bowel carcinoma. METHODS: We performed a DNA- based...

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Detalles Bibliográficos
Autores principales: Quaas, Alexander, Heydt, Carina, Waldschmidt, Dirk, Alakus, Hakan, Zander, Thomas, Goeser, Tobias, Kasper, Philipp, Bruns, Christiane, Brunn, Anna, Roth, Wilfried, Hartmann, Nils, Bunck, Anne, Schmidt, Matthias, Buettner, Reinhard, Merkelbach-Bruse, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360678/
https://www.ncbi.nlm.nih.gov/pubmed/30717682
http://dx.doi.org/10.1186/s12876-019-0942-z