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Tolerogenic XCR1(+) dendritic cell population is dysregulated in HLA-B27 transgenic rat model of spondyloarthritis

BACKGROUND: Spondyloarthritis (SpA) is a chronic inflammatory disease affecting primarily axial and peripheral joints and sometimes also extra-articular organs, such as the gut. Rats transgenic for HLA-B27 and human β2-microglobulin (B27-Tg rat) develop clinical manifestations resembling human disea...

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Detalles Bibliográficos
Autores principales: Ermoza, Kétia, Glatigny, Simon, Jah, Nadège, Camilo, Vânia, Mambu Mambueni, Hendrick, Araujo, Luiza M., Chiocchia, Gilles, Breban, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360689/
https://www.ncbi.nlm.nih.gov/pubmed/30717755
http://dx.doi.org/10.1186/s13075-019-1827-9