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Tolerogenic XCR1(+) dendritic cell population is dysregulated in HLA-B27 transgenic rat model of spondyloarthritis
BACKGROUND: Spondyloarthritis (SpA) is a chronic inflammatory disease affecting primarily axial and peripheral joints and sometimes also extra-articular organs, such as the gut. Rats transgenic for HLA-B27 and human β2-microglobulin (B27-Tg rat) develop clinical manifestations resembling human disea...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360689/ https://www.ncbi.nlm.nih.gov/pubmed/30717755 http://dx.doi.org/10.1186/s13075-019-1827-9 |