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Investigation of multi-trait associations using pathway-based analysis of GWAS summary statistics

BACKGROUND: Genome-wide association studies (GWAS) have been successful in identifying disease-associated genetic variants. Recently, an increasing number of GWAS summary statistics have been made available to the research community, providing extensive repositories for studies of human complex dise...

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Detalles Bibliográficos
Autores principales: Pei, Guangsheng, Sun, Hua, Dai, Yulin, Liu, Xiaoming, Zhao, Zhongming, Jia, Peilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360716/
https://www.ncbi.nlm.nih.gov/pubmed/30712509
http://dx.doi.org/10.1186/s12864-018-5373-7