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Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrP(CWD) deposition in orally infected white-tailed deer
BACKGROUND: Chronic wasting disease (CWD) is a prion disease affecting members of the Cervidae family. PrP(C) primary structures play a key role in CWD susceptibility resulting in extended incubation periods and regulating the propagation of CWD strains. We analyzed the distribution of abnormal prio...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360794/ https://www.ncbi.nlm.nih.gov/pubmed/30717795 http://dx.doi.org/10.1186/s12917-019-1794-z |