Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrP(CWD) deposition in orally infected white-tailed deer

BACKGROUND: Chronic wasting disease (CWD) is a prion disease affecting members of the Cervidae family. PrP(C) primary structures play a key role in CWD susceptibility resulting in extended incubation periods and regulating the propagation of CWD strains. We analyzed the distribution of abnormal prio...

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Detalles Bibliográficos
Autores principales: Otero, Alicia, Duque Velásquez, Camilo, Johnson, Chad, Herbst, Allen, Bolea, Rosa, Badiola, Juan José, Aiken, Judd, McKenzie, Debbie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360794/
https://www.ncbi.nlm.nih.gov/pubmed/30717795
http://dx.doi.org/10.1186/s12917-019-1794-z

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