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Molecular targets for modulating the protein translation vital to proteostasis and neuron degeneration in Parkinson’s disease

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, which is characterized by the progressive loss of dopaminergic neurons in the Substantia Nigra pars compacta concomitant with Lewy body formation in affected brain areas. The detailed pathogenic mechanisms underlying th...

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Detalles Bibliográficos
Autores principales: Zhou, Zhi Dong, Selvaratnam, Thevapriya, Lee, Ji Chao Tristan, Chao, Yin Xia, Tan, Eng-King
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360798/
https://www.ncbi.nlm.nih.gov/pubmed/30740222
http://dx.doi.org/10.1186/s40035-019-0145-0