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CTCF sites display cell cycle–dependent dynamics in factor binding and nucleosome positioning

CCCTC-binding factor (CTCF) plays a key role in the formation of topologically associating domains (TADs) and loops in interphase. During mitosis TADs are absent, but how TAD formation is dynamically controlled during the cell cycle is not known. Several contradicting observations have been made reg...

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Detalles Bibliográficos
Autores principales: Oomen, Marlies E., Hansen, Anders S., Liu, Yu, Darzacq, Xavier, Dekker, Job
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360813/
https://www.ncbi.nlm.nih.gov/pubmed/30655336
http://dx.doi.org/10.1101/gr.241547.118