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Systematic interrogation of human promoters

Despite much research, our understanding of the architecture and cis-regulatory elements of human promoters is still lacking. Here, we devised a high-throughput assay to quantify the activity of approximately 15,000 fully designed sequences that we integrated and expressed from a fixed location with...

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Detalles Bibliográficos
Autores principales: Weingarten-Gabbay, Shira, Nir, Ronit, Lubliner, Shai, Sharon, Eilon, Kalma, Yael, Weinberger, Adina, Segal, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360817/
https://www.ncbi.nlm.nih.gov/pubmed/30622120
http://dx.doi.org/10.1101/gr.236075.118