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Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis

A wide range of genetic mouse models is available to help researchers dissect human disease mechanisms. Each type of model has its own distinctive characteristics arising from the nature of the introduced mutation, as well as from the specific changes to the gene of interest. Here, we review the cur...

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Detalles Bibliográficos
Autores principales: De Giorgio, Francesca, Maduro, Cheryl, Fisher, Elizabeth M. C., Acevedo-Arozena, Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361152/
https://www.ncbi.nlm.nih.gov/pubmed/30626575
http://dx.doi.org/10.1242/dmm.037424