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Transgenic and physiological mouse models give insights into different aspects of amyotrophic lateral sclerosis
A wide range of genetic mouse models is available to help researchers dissect human disease mechanisms. Each type of model has its own distinctive characteristics arising from the nature of the introduced mutation, as well as from the specific changes to the gene of interest. Here, we review the cur...
Autores principales: | De Giorgio, Francesca, Maduro, Cheryl, Fisher, Elizabeth M. C., Acevedo-Arozena, Abraham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361152/ https://www.ncbi.nlm.nih.gov/pubmed/30626575 http://dx.doi.org/10.1242/dmm.037424 |
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