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Photoreceptor degeneration in microphthalmia (Mitf) mice: partial rescue by pigment epithelium-derived factor

Dysfunction and loss of the retinal pigment epithelium (RPE) are hallmarks of retinal degeneration, but the underlying pathogenetic processes are only partially understood. Using mice with a null mutation in the transcription factor gene Mitf, in which RPE deficiencies are associated with retinal de...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Yang, Juan, Geng, Huiqin, Li, Liping, Li, Jinyang, Cheng, Bing, Ma, Xiaoyin, Li, Huirong, Hou, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361154/
https://www.ncbi.nlm.nih.gov/pubmed/30651300
http://dx.doi.org/10.1242/dmm.035642