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Photoreceptor degeneration in microphthalmia (Mitf) mice: partial rescue by pigment epithelium-derived factor
Dysfunction and loss of the retinal pigment epithelium (RPE) are hallmarks of retinal degeneration, but the underlying pathogenetic processes are only partially understood. Using mice with a null mutation in the transcription factor gene Mitf, in which RPE deficiencies are associated with retinal de...
Autores principales: | Chen, Yu, Yang, Juan, Geng, Huiqin, Li, Liping, Li, Jinyang, Cheng, Bing, Ma, Xiaoyin, Li, Huirong, Hou, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361154/ https://www.ncbi.nlm.nih.gov/pubmed/30651300 http://dx.doi.org/10.1242/dmm.035642 |
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