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Modelling pancreatic β-cell inflammation in zebrafish identifies the natural product wedelolactone for human islet protection

Islet inflammation and cytokine production are implicated in pancreatic β-cell dysfunction and diabetes pathogenesis. However, we lack therapeutics to protect the insulin-producing β-cells from inflammatory damage. Closing this clinical gap requires the establishment of new disease models of islet i...

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Detalles Bibliográficos
Autores principales:	Delgadillo-Silva, Luis Fernando, Tsakmaki, Anastasia, Akhtar, Nadeem, Franklin, Zara J., Konantz, Judith, Bewick, Gavin A., Ninov, Nikolay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361155/ https://www.ncbi.nlm.nih.gov/pubmed/30679186 http://dx.doi.org/10.1242/dmm.036004

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