An exonic splicing enhancer mutation in DUOX2 causes aberrant alternative splicing and severe congenital hypothyroidism in Bama pigs

Pigs share many similarities with humans in terms of anatomy, physiology and genetics, and have long been recognized as important experimental animals in biomedical research. Using an N-ethyl-N-nitrosourea (ENU) mutagenesis screen, we previously identified a large number of pig mutants, which could...

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Detalles Bibliográficos
Autores principales: Cao, Chunwei, Zhang, Ying, Jia, Qitao, Wang, Xiao, Zheng, Qiantao, Zhang, Hongyong, Song, Ruigao, Li, Yongshun, Luo, Ailing, Hong, Qianlong, Qin, Guosong, Yao, Jing, Zhang, Nan, Wang, Yanfang, Wang, Hongmei, Zhou, Qi, Zhao, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361156/
https://www.ncbi.nlm.nih.gov/pubmed/30651277
http://dx.doi.org/10.1242/dmm.036616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361156/
https://www.ncbi.nlm.nih.gov/pubmed/30651277
http://dx.doi.org/10.1242/dmm.036616

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