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The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch

The development of the aortic arch is a complex process that involves remodeling of the bilaterally symmetrical pharyngeal arch arteries (PAAs) into the mature asymmetric aortic arch. Retinoic acid signaling is a key regulator of this process by directing patterning of the second heart field (SHF),...

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Detalles Bibliográficos
Autores principales: Sugrue, Kelsey F., Sarkar, Anjali A., Leatherbury, Linda, Zohn, Irene E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361158/
https://www.ncbi.nlm.nih.gov/pubmed/30578278
http://dx.doi.org/10.1242/dmm.036491