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The ubiquitin ligase HECTD1 promotes retinoic acid signaling required for development of the aortic arch
The development of the aortic arch is a complex process that involves remodeling of the bilaterally symmetrical pharyngeal arch arteries (PAAs) into the mature asymmetric aortic arch. Retinoic acid signaling is a key regulator of this process by directing patterning of the second heart field (SHF),...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361158/ https://www.ncbi.nlm.nih.gov/pubmed/30578278 http://dx.doi.org/10.1242/dmm.036491 |