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Integral gene drives for population replacement

A first generation of CRISPR-based gene drives has now been tested in the laboratory in a number of organisms, including malaria vector mosquitoes. Challenges for their use in the area-wide genetic control of vector-borne disease have been identified, including the development of target site resista...

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Detalles Bibliográficos
Autores principales: Nash, Alexander, Urdaneta, Giulia Mignini, Beaghton, Andrea K., Hoermann, Astrid, Papathanos, Philippos Aris, Christophides, George K., Windbichler, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361204/
https://www.ncbi.nlm.nih.gov/pubmed/30498016
http://dx.doi.org/10.1242/bio.037762