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Integral gene drives for population replacement
A first generation of CRISPR-based gene drives has now been tested in the laboratory in a number of organisms, including malaria vector mosquitoes. Challenges for their use in the area-wide genetic control of vector-borne disease have been identified, including the development of target site resista...
Autores principales: | Nash, Alexander, Urdaneta, Giulia Mignini, Beaghton, Andrea K., Hoermann, Astrid, Papathanos, Philippos Aris, Christophides, George K., Windbichler, Nikolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361204/ https://www.ncbi.nlm.nih.gov/pubmed/30498016 http://dx.doi.org/10.1242/bio.037762 |
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