Folic acid modifies the shape of epithelial cells during morphogenesis via a Folr1 and MLCK dependent mechanism

Folic acid supplementation can prevent neural tube defects, but the specific molecular mechanisms by which it does have not been elucidated. During neural plate morphogenesis, epithelial cell apical constriction cooperates with other events to drive tissue-bending, and when defective, can result in...

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Detalles Bibliográficos
Autores principales: Martin, Jessica B., Muccioli, Maria, Herman, Kenneth, Finnell, Richard H., Plageman, Timothy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361208/
https://www.ncbi.nlm.nih.gov/pubmed/30670450
http://dx.doi.org/10.1242/bio.041160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361208/
https://www.ncbi.nlm.nih.gov/pubmed/30670450
http://dx.doi.org/10.1242/bio.041160

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