Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases

Members of the Flaviviridae family constitute a severe risk to human health. Whilst effective drugs have been developed against the hepacivirus HCV, no antiviral therapy is currently available for any other viruses, including the flaviviruses dengue (DENV), West Nile and Zika viruses. The RNA-depend...

Descripción completa

Detalles Bibliográficos
Autores principales: Riccio, Federica, Talapatra, Sandeep K., Oxenford, Sally, Angell, Richard, Mazzon, Michela, Kozielski, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361211/
https://www.ncbi.nlm.nih.gov/pubmed/30602529
http://dx.doi.org/10.1242/bio.037663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361211/
https://www.ncbi.nlm.nih.gov/pubmed/30602529
http://dx.doi.org/10.1242/bio.037663

Ejemplares similares