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The role of retrograde intraflagellar transport genes in aminoglycoside-induced hair cell death

Sensory hair cells are susceptible to numerous insults, including certain therapeutic medications like aminoglycoside antibiotics, and hearing and balance disorders are often a dose-limiting side effect of these medications. We show that mutations in multiple genes in both the retrograde intraflagel...

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Detalles Bibliográficos
Autores principales: Stawicki, Tamara M., Linbo, Tor, Hernandez, Liana, Parkinson, Lauren, Bellefeuille, Danielle, Rubel, Edwin W., Raible, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361216/
https://www.ncbi.nlm.nih.gov/pubmed/30578252
http://dx.doi.org/10.1242/bio.038745