Cargando…

SKEMPI 2.0: an updated benchmark of changes in protein–protein binding energy, kinetics and thermodynamics upon mutation

MOTIVATION: Understanding the relationship between the sequence, structure, binding energy, binding kinetics and binding thermodynamics of protein–protein interactions is crucial to understanding cellular signaling, the assembly and regulation of molecular complexes, the mechanisms through which mut...

Descripción completa

Detalles Bibliográficos
Autores principales: Jankauskaitė, Justina, Jiménez-García, Brian, Dapkūnas, Justas, Fernández-Recio, Juan, Moal, Iain H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361233/
https://www.ncbi.nlm.nih.gov/pubmed/30020414
http://dx.doi.org/10.1093/bioinformatics/bty635