Cargando…

Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes

The life cycle of cultured proliferating cells is characterized by fluctuations in cell population density induced by periodic subculturing. This leads to corresponding changes in micro- and macroenvironment of the cells, accompanied by altered cellular metabolism, growth rate and locomotion. Studyi...

Descripción completa

Detalles Bibliográficos
Autores principales: Trajkovic, Katarina, Valdez, Clarissa, Ysselstein, Daniel, Krainc, Dimitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361456/
https://www.ncbi.nlm.nih.gov/pubmed/30716115
http://dx.doi.org/10.1371/journal.pone.0211727