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Fluctuations in cell density alter protein markers of multiple cellular compartments, confounding experimental outcomes
The life cycle of cultured proliferating cells is characterized by fluctuations in cell population density induced by periodic subculturing. This leads to corresponding changes in micro- and macroenvironment of the cells, accompanied by altered cellular metabolism, growth rate and locomotion. Studyi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361456/ https://www.ncbi.nlm.nih.gov/pubmed/30716115 http://dx.doi.org/10.1371/journal.pone.0211727 |