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Impact of UGT1A1 genetic polymorphism on toxicity in unresectable pancreatic cancer patients undergoing FOLFIRINOX

Studies have indicated an association between UDP‐glucuronosyltransferase‐1A1 (UGT1A1) genetic polymorphisms and irinotecan‐induced toxicity. We undertook this study to investigate the association between UGT1A1 genetic polymorphisms and toxicity in patients treated with the FOLFIRINOX (comprising o...

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Detalles Bibliográficos
Autores principales: Shirasu, Hiromichi, Todaka, Akiko, Omae, Katsuhiro, Fujii, Hirofumi, Mizuno, Nobumasa, Ozaka, Masato, Ueno, Hideki, Kobayashi, Satoshi, Uesugi, Kazuhiro, Kobayashi, Noritoshi, Hayashi, Hideyuki, Sudo, Kentaro, Okano, Naohiro, Horita, Yosuke, Kamei, Keiko, Yukisawa, Seigo, Kobayashi, Marina, Fukutomi, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361560/
https://www.ncbi.nlm.nih.gov/pubmed/30447099
http://dx.doi.org/10.1111/cas.13883