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Potent antiproliferative effect of fatty‐acid derivative AIC‐47 on leukemic mice harboring BCR‐ABL mutation

Therapy based on targeted inhibition of BCR‐ABL tyrosine kinase has greatly improved the prognosis for patients with Philadelphia chromosome (Ph)‐positive leukemia and tyrosine kinase inhibitors (TKI) have become standard therapy. However, some patients acquire resistance to TKI that is frequently a...

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Detalles Bibliográficos
Autores principales: Shinohara, Haruka, Sugito, Nobuhiko, Kuranaga, Yuki, Heishima, Kazuki, Minami, Yosuke, Naoe, Tomoki, Akao, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361563/
https://www.ncbi.nlm.nih.gov/pubmed/30548479
http://dx.doi.org/10.1111/cas.13913