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Increased nicotinamide adenine dinucleotide pool promotes colon cancer progression by suppressing reactive oxygen species level

Nicotinamide adenine dinucleotide (NAD) exists in an oxidized form (NAD(+)) and a reduced form (NADH). NAD (+) plays crucial roles in cancer metabolism, including in cellular signaling, energy production and redox regulation. However, it remains unclear whether NAD(H) pool size (NAD (+) and NADH) co...

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Detalles Bibliográficos
Autores principales: Hong, Sun M., Hwang, Sung W., Wang, Taejun, Park, Chang W., Ryu, Yeon‐Mi, Jung, Jin‐Hak, Shin, Ji H., Kim, Sang‐Yeob, Lee, Jong L., Kim, Chan W., Yoon, Gyesoon, Kim, Ki H., Myung, Seung‐Jae, Choi, Kwan Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361564/
https://www.ncbi.nlm.nih.gov/pubmed/30457689
http://dx.doi.org/10.1111/cas.13886