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Identification of genes involved in the regulation of TERT in hepatocellular carcinoma

Telomerase reverse transcriptase (TERT) promotes immortalization by protecting telomeres in cancer cells. Mutation of the TERT promoter is one of the most common genetic alterations in hepatocellular carcinoma (HCC), indicating that TERT upregulation is a critical event in hepatocarcinogenesis. Regu...

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Detalles Bibliográficos
Autores principales: Amisaki, Masataka, Tsuchiya, Hiroyuki, Sakabe, Tomohiko, Fujiwara, Yoshiyuki, Shiota, Goshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361581/
https://www.ncbi.nlm.nih.gov/pubmed/30447097
http://dx.doi.org/10.1111/cas.13884