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Collider bias and the apparent protective effect of glucose-6-phosphate dehydrogenase deficiency on cerebral malaria

Case fatality rates in severe falciparum malaria depend on the pattern and degree of vital organ dysfunction. Recent large-scale case-control analyses of pooled severe malaria data reported that glucose-6-phosphate dehydrogenase deficiency (G6PDd) was protective against cerebral malaria but increase...

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Detalles Bibliográficos
Autores principales: Watson, James A, Leopold, Stije J, Simpson, Julie A, Day, Nicholas PJ, Dondorp, Arjen M, White, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361583/
https://www.ncbi.nlm.nih.gov/pubmed/30688212
http://dx.doi.org/10.7554/eLife.43154