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Significant antitumor effect of an antibody against TMEM180, a new colorectal cancer‐specific molecule

The present state of therapy for colorectal cancer (CRC) is far from satisfactory, highlighting the need for new targets for this disease. We identified a new CRC‐specific molecule, TMEM180, a predicted 11‐pass transmembrane protein that apparently functions as a cation symporter. We developed an an...

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Detalles Bibliográficos
Autores principales: Yasunaga, Masahiro, Saijou, Shinji, Hanaoka, Shingo, Anzai, Takahiro, Tsumura, Ryo, Matsumura, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361608/
https://www.ncbi.nlm.nih.gov/pubmed/30537002
http://dx.doi.org/10.1111/cas.13907