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Drug nanoclusters formed in confined nano-cages of CD-MOF: dramatic enhancement of solubility and bioavailability of azilsartan

Tremendous efforts have been devoted to the enhancement of drug solubility using nanotechnologies, but few of them are capable to produce drug particles with sizes less than a few nanometers. This challenge has been addressed here by using biocompatible versatile γ-cyclodextrin (γ-CD) metal-organic...

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Detalles Bibliográficos
Autores principales: He, Yuanzhi, Zhang, Wei, Guo, Tao, Zhang, Guoqing, Qin, Wei, Zhang, Liu, Wang, Caifen, Zhu, Weifeng, Yang, Ming, Hu, Xiaoxiao, Singh, Vikramjeet, Wu, Li, Gref, Ruxandra, Zhang, Jiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361728/
https://www.ncbi.nlm.nih.gov/pubmed/30766781
http://dx.doi.org/10.1016/j.apsb.2018.09.003