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Secretion of IL-1β From Monocytes in Gout Is Redox Independent

The pro-inflammatory cytokine interleukin-1β (IL-1β) plays important roles in immunity but is also implicated in autoimmune disease. The most well-established mechanism of IL-1β secretion is via activation of the NOD-like receptor family pyrin domain containing-3 (NLRP3) inflammasome which requires...

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Detalles Bibliográficos
Autores principales: Alberts, Ben M., Bruce, Connor, Basnayake, Kolitha, Ghezzi, Pietro, Davies, Kevin A., Mullen, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361747/
https://www.ncbi.nlm.nih.gov/pubmed/30761138
http://dx.doi.org/10.3389/fimmu.2019.00070