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Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes

Osteoarthritis (OA) is a common joint disease in the elderly population. Its development has been reported to be associated with cartilage degradation and inflammatory responses. Schisandrin A, a bioactive lignin in Schisandra sphenanthera, has shown its anti-inflammatory potential in various inflam...

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Detalles Bibliográficos
Autores principales: Tu, Chang, Huang, Xiaojian, Xiao, Yifan, Song, Mingyu, Ma, Yongzhuang, Yan, Jiyuan, You, Hongbo, Wu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361757/
https://www.ncbi.nlm.nih.gov/pubmed/30761007
http://dx.doi.org/10.3389/fphar.2019.00041