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Brain Endothelium: The “Innate Immunity Response Hypothesis” in Cerebral Malaria Pathogenesis

Cerebral malaria (CM) is a life-threatening neurological syndrome caused by Plasmodium falciparum infection afflicting mainly children in Africa. Current pathogenesis models implicate parasite and host-derived factors in impairing brain vascular endothelium (BVE) integrity. Sequestration of Plasmodi...

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Detalles Bibliográficos
Autores principales: Pais, Teresa F., Penha-Gonçalves, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361776/
https://www.ncbi.nlm.nih.gov/pubmed/30761156
http://dx.doi.org/10.3389/fimmu.2018.03100