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Brain Endothelium: The “Innate Immunity Response Hypothesis” in Cerebral Malaria Pathogenesis
Cerebral malaria (CM) is a life-threatening neurological syndrome caused by Plasmodium falciparum infection afflicting mainly children in Africa. Current pathogenesis models implicate parasite and host-derived factors in impairing brain vascular endothelium (BVE) integrity. Sequestration of Plasmodi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361776/ https://www.ncbi.nlm.nih.gov/pubmed/30761156 http://dx.doi.org/10.3389/fimmu.2018.03100 |