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Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome

Osteoarthritis (OA) is an inflammatory condition still lacking effective treatments. Mesenchymal stem/stromal cells (MSCs) have been successfully employed in pre-clinical models aiming to resurface the degenerated cartilage. In early-phase clinical trials, intra-articular (IA) administration of MSCs...

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Detalles Bibliográficos
Autores principales: Mancuso, Patrizio, Raman, Swarna, Glynn, Aoife, Barry, Frank, Murphy, J. Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361779/
https://www.ncbi.nlm.nih.gov/pubmed/30761298
http://dx.doi.org/10.3389/fbioe.2019.00009