Raising the Diversity of Ugi Reactions Through Selective Alkylations and Allylations of Ugi Adducts

We report here selective Tsuji-Trost type allylation of Ugi adducts using a strategy based on the enhanced nucleophilicity of amide dianions. Ugi adducts derived from aromatic aldehydes were easily allylated at their peptidyl position with allyl acetate in the presence of palladium catalysts. These...

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Detalles Bibliográficos
Autores principales: Zidan, Alaa, El-Naggar, Abeer M., Abd El-Sattar, Nour E. A., Ali, Ali Khalil, El Kaïm, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361783/
https://www.ncbi.nlm.nih.gov/pubmed/30761290
http://dx.doi.org/10.3389/fchem.2019.00020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361783/
https://www.ncbi.nlm.nih.gov/pubmed/30761290
http://dx.doi.org/10.3389/fchem.2019.00020

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