Insight Into the Binding Mechanism of p53/pDIQ-MDMX/MDM2 With the Interaction Entropy Method

The study of the p53-MDMX/MDM2 binding sites is a research hotspot for tumor drug design. The inhibition of p53-targeted MDMX/MDM2 has become an effective approach in anti-tumor drug development. In this paper, a theoretically rigorous and computationally accurate method, namely, the interaction ent...

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Detalles Bibliográficos
Autores principales: Li, Mengxin, Cong, Yalong, Li, Yuchen, Zhong, Susu, Wang, Ran, Li, Hao, Duan, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361799/
https://www.ncbi.nlm.nih.gov/pubmed/30761293
http://dx.doi.org/10.3389/fchem.2019.00033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361799/
https://www.ncbi.nlm.nih.gov/pubmed/30761293
http://dx.doi.org/10.3389/fchem.2019.00033

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