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Massive B-Cell Infiltration and Organization Into Artery Tertiary Lymphoid Organs in the Aorta of Large Vessel Giant Cell Arteritis

Giant cell arteritis (GCA) can be classified into Cranial(C)-GCA and Large Vessel(LV)-GCA. Based on analysis of temporal arteries, GCA is postulated to be T-cell-mediated. Recently, a disturbed B-cell homeostasis was documented in newly diagnosed GCA patients. In the current study, we assessed the p...

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Detalles Bibliográficos
Autores principales: Graver, Jacoba C., Boots, Annemieke M. H., Haacke, Erlin A., Diepstra, Arjan, Brouwer, Elisabeth, Sandovici, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361817/
https://www.ncbi.nlm.nih.gov/pubmed/30761147
http://dx.doi.org/10.3389/fimmu.2019.00083