Oxidative Stress Regulated Iron Regulatory Protein IRP2 Through FBXL5-Mediated Ubiquitination-Proteasome Way in SH-SY5Y Cells

Iron regulatory protein 2 (IRP2) plays a key role in the cellular iron homeostasis and could be regulated by a variety of factors, such as oxidative stress, hypoxia and iron, etc. IRP2 depletion results in neurodegenerative movement disorder with the loss of neurons and accumulations of iron. Since...

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Detalles Bibliográficos
Autores principales: Jiao, Qian, Du, Xixun, Wei, Jie, Li, Yong, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361836/
https://www.ncbi.nlm.nih.gov/pubmed/30760976
http://dx.doi.org/10.3389/fnins.2019.00020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361836/
https://www.ncbi.nlm.nih.gov/pubmed/30760976
http://dx.doi.org/10.3389/fnins.2019.00020

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