BRD4 Inhibition Enhances Azacitidine Efficacy in Acute Myeloid Leukemia and Myelodysplastic Syndromes

Myelodysplastic syndromes (MDS) are clonal hematopoietic stem cell-based disorders characterized by ineffective hematopoiesis, increased genomic instability and a tendency to progress toward acute myeloid leukemia (AML). MDS and AML cells present genetic and epigenetic abnormalities and, due to the...

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Detalles Bibliográficos
Autores principales: Pericole, Fernando Vieira, Lazarini, Mariana, de Paiva, Luciana Bueno, Duarte, Adriana da Silva Santos, Vieira Ferro, Karla Priscila, Niemann, Fernanda Soares, Roversi, Fernanda Marconi, Olalla Saad, Sara Teresinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361844/
https://www.ncbi.nlm.nih.gov/pubmed/30761268
http://dx.doi.org/10.3389/fonc.2019.00016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361844/
https://www.ncbi.nlm.nih.gov/pubmed/30761268
http://dx.doi.org/10.3389/fonc.2019.00016

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