Autoantibodies Against C3b—Functional Consequences and Disease Relevance

The complement component C3 is at the heart of the complement cascade. It is a complex protein, which generates different functional activated fragments (C3a, C3b, iC3b, C3c, C3d). C3b is a constituent of the alternative pathway C3 convertase (C3bBb), binds multiple regulators, and receptors, affect...

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Detalles Bibliográficos
Autores principales: Vasilev, Vasil V., Radanova, Maria, Lazarov, Valentin J., Dragon-Durey, Marie-Agnes, Fremeaux-Bacchi, Veronique, Roumenina, Lubka T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361862/
https://www.ncbi.nlm.nih.gov/pubmed/30761135
http://dx.doi.org/10.3389/fimmu.2019.00064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361862/
https://www.ncbi.nlm.nih.gov/pubmed/30761135
http://dx.doi.org/10.3389/fimmu.2019.00064

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