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Clinical significance of filamin A in patients with acromegaly and its association with somatostatin and dopamine receptor profiles

Filamin-A (FLNA) plays a crucial role in somatostatin receptor (sst) subtype-2 signaling in somatotropinomas. Our objective was to investigate the in vivo association between FLNA and sst2 expression, sst5 expression, dopamine receptor subtype-2 (D2) expression, somatostatin receptor ligand (SRL) re...

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Detalles Bibliográficos
Autores principales: Coelho, Maria Caroline Alves, Vasquez, Marina Lipkin, Wildemberg, Luiz Eduardo, Vázquez-Borrego, Mari C., Bitana, Luciana, Camacho, Aline Helen da Silva, Silva, Débora, Ogino, Liana Lumi, Ventura, Nina, Sánchez-Sánchez, Rafael, Chimelli, Leila, Kasuki, Leandro, Luque, Raul M., Gadelha, Mônica R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361919/
https://www.ncbi.nlm.nih.gov/pubmed/30718563
http://dx.doi.org/10.1038/s41598-018-37692-3