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Activity-induced MEMRI cannot detect functional brain anomalies in the APPxPS1-Ki mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is the most common cause of dementia. Aside neuropathological lesions, abnormal neuronal activity and brain metabolism are part of the core symptoms of the disease. Activity-induced Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) has been proposed as a powerful approac...

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Detalles Bibliográficos
Autores principales: Androuin, Alexandre, Abada, Yah-se, Ly, Myriam, Santin, Mathieu, Petiet, Alexandra, Epelbaum, Stéphane, Bertrand, Anne, Delatour, Benoît
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361936/
https://www.ncbi.nlm.nih.gov/pubmed/30718666
http://dx.doi.org/10.1038/s41598-018-37980-y