A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy

Both targeted therapy and immunotherapy have been used successfully to treat melanoma, but the development of resistance and poor response rates to the individual therapies has limited their success. Designing rational combinations of targeted therapy and immunotherapy may overcome these obstacles,...

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Detalles Bibliográficos
Autores principales: Lelliott, Emily J., Cullinane, Carleen, Martin, Claire A., Walker, Rachael, Ramsbottom, Kelly M., Souza-Fonseca-Guimaraes, Fernando, Abuhammad, Shatha, Michie, Jessica, Kirby, Laura, Young, Richard J., Slater, Alison, Lau, Peter, Meeth, Katrina, Oliaro, Jane, Haynes, Nicole, McArthur, Grant A., Sheppard, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361951/
https://www.ncbi.nlm.nih.gov/pubmed/30718660
http://dx.doi.org/10.1038/s41598-018-37883-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361951/
https://www.ncbi.nlm.nih.gov/pubmed/30718660
http://dx.doi.org/10.1038/s41598-018-37883-y

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