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Metformin enhances the radiosensitizing effect of cisplatin in non-small cell lung cancer cell lines with different cisplatin sensitivities

Cisplatin is an extensively used chemotherapeutic drug for lung cancer, but the development of resistance decreases its effectiveness in the treatments of non-small cell lung cancer (NSCLC). In this study, we examined the effects of metformin, a widely used antidiabetic drug, on cisplatin radiosensi...

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Detalles Bibliográficos
Autores principales: Riaz, Muhammad Assad, Sak, Ali, Erol, Yasin Bahadir, Groneberg, Michael, Thomale, Jürgen, Stuschke, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361966/
https://www.ncbi.nlm.nih.gov/pubmed/30718758
http://dx.doi.org/10.1038/s41598-018-38004-5